c-MET anticorps (Catalytic Domain)

N° du produit ABIN3031757

L’anticorps Souris Monoclonal anti-c-MET a été validé pour WB, ELISA, IHC et IF. Il convient pour détecter c-MET dans des échantillons de Humain et Souris.

Aperçu rapide pour c-MET anticorps (Catalytic Domain) (ABIN3031757)

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp c-MET est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 4AT44

Détail du produit anti-c-MET anticorps

Épitope: Catalytic Domain

Purification: Purified

Immunogène: This MET antibody was produced from mice immunized with purified recombinant protein encoding the catalytic domain of human MET/HGFR.

Isotype: IgG1

Information d'application

Indications d'application: Titration of the MET antibody (HGFR) may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:100,IHC (Paraffin): 1:25-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MET antibody (HGFR) and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur c-MET

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Autre désignation: MET (HGFR)

Sujet: The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P08581

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor